VANCOUVER, British Columbia, Sept. 26, 2017 (GLOBE NEWSWIRE) — Jeffery Bacha, CEO of DelMar Pharmaceuticals Inc. (NASDAQ:DMPI) interviews on the Uptick Network Stock Day Podcast with host Everett Jolly. Mr. Bacha discusses DelMar’s VOL-083 phase 3 clinical trial chemotherapy that has recently launched and how this trial has progressed since its launch. Delmar recently completed a financing, and Mr. Bacha explains how this financing benefits the company and supports DelMar’s clinical trials. Furthermore, Mr. Bacha discusses the major milestones for the future of DelMar and what the company is looking to accomplish with its research and clinical trials.
In closing, CEO Jeffery Bacha states, “There is a wonderful story about a fellow who is a glioblastoma patient and he was treated the Monday, Tuesday and Wednesday prior to the weekend that he and his wife joined us on what’s called The Ride to Concur Cancer. He rode over 250 kilometers from Vancouver British Columbia to Seattle and he’s on our drug and he’s tolerating it very well, Mr. Bacha continues, “It is amazing to be a part of that with him. Just knowing that this is someone that we are hopefully going to be able to help and being a part of that puts this into perspective of how important this is and we are looking to do that for many more patients.
To listen to the full interview please click here.
The Company’s current pipeline is based around VAL-083, a “first-in-class,” small-molecule chemotherapeutic with a novel mechanism of action that has demonstrated clinical activity against a range of cancers including central nervous system, ovarian and other solid tumors (e.g. NSCLC, bladder cancer, head & neck) in U.S. clinical trials sponsored by the NCI. Based on DelMar’s internal research programs and these prior NCI-sponsored clinical studies, the Company is conducting clinical trials to support the development and commercialization of VAL-083 across multiple oncology indications to solve significant unmet medical needs.
The STAR-3 trial is a multi-center, pivotal, randomized Phase 3 clinical study in bevacizumab (Avastin®) recurrent GBM. Outcomes in DelMar’s recent Phase 1-2 clinical trials suggest that VAL-083 may offer a clinically meaningful survival benefit for this patient population.
VAL-083 is also being studied in two collaborator-supported, biomarker driven, Phase 2 clinical trials for MGMT-unmethylated GBM as a potential alternative for the majority of GBM patients whose tumors exhibit high expression of MGMT, a biomarker correlated with resistance to the current standard-of-care chemotherapy. Overcoming MGMT-mediated resistance represents a significant unmet medical need in the treatment of GBM.
The VAL-083 REPROVe trial will explore VAL-083 in platinum-resistant ovarian cancer. Resistance to platinum-based chemotherapy represents a significant unmet medical need in the treatment of ovarian cancer.
Further information on DelMar’s clinical trials can be found here on clinicaltrials.gov.
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