InMed Expands on Announcement of Cannabinol (CBN) Therapeutic Leadership with New Website Content and CEO Interview

Vancouver, BC – January 21, 2020 – InMed Pharmaceuticals Inc. (“InMed” or the “Company”) (TSX:IN; OTCQX:IMLFF), a clinical stage biopharmaceutical company developing medications targeting diseases with high unmet medical need and leading the way in the clinical development of cannabinol (CBN), today published additional information describing in detail its leading cannabinol-based therapeutics programs on its corporate website at

“Having revealed cannabinol, or CBN, as the active pharmaceutical ingredient in InMed’s lead product candidates INM-755 and INM-088, we have now provided additional information on the potential for CBN formulations to treat disease.” commented InMed CEO, Eric A. Adams. “The initiation of clinical trials with INM-755 is just one of several examples of the significant progress the InMed team has made in advancing our understanding of CBN’s therapeutic benefits as well as advancing our biosynthesis program in recent months.”

Details of InMed’s progress and milestones can be found in InMed’s 2020 CEO Letter to Shareholders at: InMed 2020 Shareholders Letter

Mr. Adams was also recently interviewed by Edison Research Analyst Maxim Jacobs on the topic of the therapeutic potential of CBN and InMed’s development pipeline. That interview is available at: CEO Interview

Yesterday at the EB World Congress in London, UK, InMed’s scientific team officially revealed CBN as the active pharmaceutical ingredient (API) in INM-755 while exhibiting preclinical data in support of the INM-755 program in EB. InMed’s EB2020 scientific posters can be viewed here.

CBN is one of several rare cannabinoids found in the cannabis plant at significantly lower levels relative to the more commonly known tetrahydrocannabinol (THC) and cannabidiol (CBD). Despite structural similarity and common origin, different cannabinoids have been observed to have distinct physiological properties, including therapeutic potential in specific diseases and unique safety profiles. InMed’s current pipeline is comprised of cannabinol-based product candidates INM-755 for potential treatment of dermal disease, with its ongoing Phase 1 trial in epidermolysis bullosa (EB), and INM-088 for potential treatment of ocular disease, initially targeting glaucoma.

INM-755 is being developed as InMed’s lead dermatological product candidate for the treatment of symptoms related to EB, a rare genetic skin disease characterized by fragile skin that can lead to extensive wounds and blistering. INM-755 is formulated as a CBN-based topical cream. In addition to relief of symptoms, including inflammation and pain, InMed believes INM-755 may enhance skin integrity in a subset of EB Simplex patients. Following regulatory and ethics committee approval in December 2019, InMed initiated a Phase 1 clinical trial for INM-755 in healthy volunteers.

CBN is also the API in InMed’s second product candidate, INM-088, being investigated as a potential treatment for ocular disease. INM-088 is in preclinical testing and advanced formulation development with an aim to decrease intraocular pressure and provide neuroprotection for individuals suffering from glaucoma.

Both INM-755 and INM-088 are designed for topical administration at the disease site, seeking to avoid potential side effects related to systemic exposure. InMed has filed patents to protect its use of CBN and other rare cannabinoids to treat these and other potential diseases, as well as patents directed towards its proprietary biosynthesis platform.

About InMed: InMed Pharmaceuticals is a clinical stage biopharmaceutical company developing a pipeline of cannabinoid-based medications, initially focused on the therapeutic benefits of cannabinol (CBN), in diseases with high unmet medical need. The Company is dedicated to delivering new therapeutic alternatives to patients that may benefit from cannabinoid-based medicines. For more information, visit

About Cannabinol (CBN): CBN is a rare cannabinoid with unique physiological properties that may result in distinct therapeutic and safety characteristics relative to the more commonly known cannabinoids tetrahydrocannabinol (THC) and cannabidiol (CBD). CBN occurs naturally in the cannabis plant, but typically only in trace quantities. InMed Pharmaceuticals is exploring the therapeutic potential of CBN in diseases with high unmet medical need.

About INM-755: INM-755 is a proprietary, topical, cannabinol-based cream product candidate intended as a topical therapy to treat epidermolysis bullosa (EB) and potentially other dermatological disease indications. Preclinical data demonstrate that INM-755 may help relieve hallmark EB symptoms, such as inflammation and pain, as well potentially restore the integrity of the skin in a subset of EB Simplex patients.

About Epidermolysis Bullosa (EB): EB is the collective name of a group of genetic disorders of connective tissues affecting individuals from birth and is characterized by fragile skin that is easily damaged, leading to extensive blistering and wounding. The blisters may appear in response to minor injury, even from heat, rubbing, scratching or adhesive tape. The disease has no definitive cure and all currently used treatments are directed towards symptom relief.

About INM-088: InMed is developing INM-088 as a cannabinol (CBN) eye drop formulation targeting reduction of the intraocular pressure associated with glaucoma as well as being designed to serve as a neuroprotectant to the retinal ganglion cells.

About Glaucoma: Glaucoma is a group of eye conditions characterized by abnormally high pressure in the eye, which can damage the membranes of the retina and the head of the optic nerve, leading to blindness. Glaucoma is the second leading cause of blindness worldwide and can occur at any age but is more common in older adults.

Investor Contact:

InMed Pharmaceuticals Inc.

Brendan Payne, Director – Investor Relations

T:         +1.604.669.7207



Edison Advisors for InMed Pharmaceuticals

Joe Green, Senior Vice President

T:         +1.646.653.7030


Cautionary Note Regarding Forward-Looking Information:

This news release contains “forward-looking information” and “forward-looking statements” (collectively, “forward-looking information”) within the meaning of applicable securities laws. Forward-looking information is based on management’s current expectations and beliefs and is subject to a number of risks and uncertainties that could cause actual results to differ materially from those described in the forward-looking statements. Forward-looking information in this news release includes statements about: leading the way in the clinical development of CBN to treat human disease; the potential for CBN formulations to treat disease; the potential for INM-755 to treat dermal disease including treating the symptoms of EB; the potential for INM-088 to treat ocular disease including glaucoma; INM-755 potentially enhancing skin integrity in a subset of EB Simplex patients; the potential for INM-088 to decrease intraocular pressure and provide neuroprotection for individuals suffering from glaucoma; the ability to avoid potential side effects related to systemic exposure via topical application of its drug candidates; potentially developing other dermatological disease indications for INM-755; and developing a proprietary biosynthesis system for the manufacturing of pharmaceutical-grade cannabinoids, as well as a pipeline of cannabinoid-based medications that target diseases with high unmet medical need.

With respect to the forward-looking information contained in this news release, InMed has made numerous assumptions regarding, among other things: continued and timely positive preclinical and clinical efficacy data; the speed of regulatory approvals; the effectiveness of patent protection; demand for InMed’s products; and continued economic and market stability. While InMed considers these assumptions to be reasonable, these assumptions are inherently subject to significant business, economic, competitive, market and social uncertainties and contingencies.

Additionally, there are known and unknown risk factors which could cause InMed’s actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking information contained herein. Known risk factors include, among others: the Phase 1 trial for INM-755 may not proceed with the anticipated timeline and structure, or at all; INM-755 may not produce the desired effects; InMed may not be able to advance its other product candidates, such as INM-088, on a timely basis, or at all; regulatory filings may not be filed or approved on a timely basis, or at all; clinical trials may not proceed as anticipated; economic or market conditions may worsen; InMed’s proprietary biosynthesis manufacturing process and drug development programs may not deliver the expected level of results; and InMed may not be able to provide new therapeutic alternatives that benefit patients via cannabinoid-based medicines. A more complete discussion of the risks and uncertainties facing InMed is disclosed in InMed’s most recent Annual Information Form and other continuous disclosure filed with Canadian securities regulatory authorities on SEDAR at

All forward-looking information herein is qualified in its entirety by this cautionary statement, and InMed disclaims any obligation to revise or update any such forward-looking information or to publicly announce the result of any revisions to any of the forward-looking information contained herein to reflect future results, events or developments, except as required by law.