LifeSciences BC > Member Announcements > Onestep Laboratories developed QuickRedTM (the first) small molecular Near Infrared nucleus stain for living cell imaging

Onestep Laboratories developed QuickRedTM (the first) small molecular Near Infrared nucleus stain for living cell imaging

The nucleus is a highly specialized organelle that serves as the information processing and administrative center of the cell. This organelle has two major functions: it stores the cell’s hereditary material, or DNA, and it coordinates the cell’s activities, which include growth, intermediary metabolism, protein synthesis, and reproduction (cell division).

The nucleus is the information center of the cell and is surrounded by a nuclear membrane in all eukaryotic organisms. It is separated from the cytoplasm by the nuclear envelope, and it houses the double-stranded, spiral-shaped deoxyribonucleic acid (DNA) molecules, which contain the genetic information necessary for the cell to retain its unique character as it grows and divides.

QuickRedTM reagent is a cell permeant stain that emits bright NIR fluorescence when bound to DNA. QuickRedTM reagent is suitable for staining nuclei in live/fixed cell preparations and tissue sections. QuickRedTM reagent also has wide applicability due to their low background and bright fluorescence. Uses include staining of nucleic acids on solid supports, pre-staining of samples for gel or capillary electrophoresis, viability detection and counterstaining in multiple-label experiments.

Different Probe Reagents of Nucleus Visualization

 

Hoechst

DAPI

Propidium Iodide

QuickRedTM

Suitability for fixed samples

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Suitability for live cell imaging

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Maintenance of Nucleus functionality

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Biocompatibility

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Quality of signal-to-noise ratio

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Nucleus binding specificity

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water solubility

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Excitation⁄emission (nm)

355/465

364/454

535/615

625/650

About Onestep Laboratories Inc.

Onestep Laboratories Inc. is dedicated to producing quality, single component QuickBlu® TMB substrate for ELISA testing. QuickBlu® single component TMB substrates have been proven to possess excellent sensitivity and lot-to-lot consistency. QuickBlu® TMB substrates are remarkably stable for up to 4 years at 2 – 8°C. The solution can be concentrated up to 10 times for easy transportation and has been patented in the United States.

Contact Information

Hao Zhang

info@1steplab.com